Treating a deadly childhood cancer with a sideways approach
Neuroblastomas are the most common cancer in infants, with about 700–800 diagnoses per year in the US, according to the American Cancer...
Mar 27
Metronomic chemotherapy offers hope for children with neuroblastoma
Despite advances in treatment, survival rates for high-risk and relapsed/refractory neuroblastoma remain dismal, and options like...
Jan 29
Why copper could be key to treating a rare childhood cancer
The survival rate for children with a rare but deadly cancer could one day be improved by adding an existing drug—which is currently used...
Dec 23, 2024
How a Penn State professor developed a cancer-fighting drug for kids
Giselle Saulnier Sholler has spent 20 years working treatments for neuroblastoma, a particularly aggressive form of early childhood...
Dec 6, 2024
Discovery of a new tumor cell type in childhood cancer
Researchers from Karolinska Institutet have made a significant breakthrough in the study of childhood neuroblastoma, a type of cancer...
Nov 1, 2024
CRISPR Plus Drug Treatment Makes Neuroblastoma Responsive to Immunotherapy
Researchers in Italy and Australia report a triple combination strategy involving CRISPR that boosts the response of neuroblastoma to...
Oct 29, 2024
Strength in numbers: Cooperative group clinical trials move the needle against pediatric cancer
Running a clinical trial requires enough patient participants to gather robust data so that researchers can draw appropriate conclusions...
Sep 16, 2024
FDA Grants Orphan Drug Designation to Opaganib in Neuroblastoma
The FDA has granted a second orphan drug designation to opaganib in oncology, this time for patients with neuroblastoma. Read more:...
Sep 13, 2024
First successful treatment of pediatric high-risk refractory neuroblastoma with PARP inhibition
Scientists and clinicians at St. Jude Children’s Research Hospital identified the genetic vulnerability BARD1 in a patient with pediatric...
Aug 30, 2024
Researchers identify malignant cells responsible for relapse in high-risk neuroblastoma
The study marks the first time that researchers identified malignant cells responsible for relapse in neuroblastoma and offers insights...
Aug 29, 2024