A new CAR-T-cell therapy tricks cancer cells with a decoy to increase treatment efficiency in B-cell Acute Lymphoblastic Leukaemia
CAR-T cell therapy has significantly improved outcomes for B-ALL patients, but relapse still occurs in over 50% of cases, leaving many...
Mar 25
Menin inhibitor clinical trial puts pediatric leukemia patient in remission
“Patient response to revumenib has been good in other clinical trials,” explains Cuglievan. “But it’s also been short-lived when used...
Dec 27, 2024
CAR-T Cell Therapy Shows EFS Benefit in Pediatric Leukemia Subset
Treatment with bicistronic CD19/CD22 CAR-T cell therapy has shown event-free survival improvements in children with relapsed or...
Dec 19, 2024
Global clinical trial shows improved survival rates for common childhood leukemia
Early study results were so promising that the trial closed early, with findings published in the New England Journal of Medicine ...
Dec 18, 2024
Researchers identify gene signature for high-risk form of T-cell acute lymphoblastic leukemia
Researchers from Children's Hospital of Philadelphia (CHOP) have discovered the underlying biology that identifies a subset of patients...
Nov 27, 2024
Increased Surveillance Recommended for Children at Risk for Hematopoietic Malignancy Predisposition
Children with a genetic risk of developing myelodysplastic syndromes (MDS) and other hematopoietic malignancies (HM), such as leukemias...
Nov 12, 2024
Even 15 Years Later, Childhood Cancer Survivors More Likely to Develop Leukemia
Childhood cancer survivors are more likely than the general population to develop subsequent leukemia, even 15 years or more after their...
Nov 7, 2024
A Tantalizing Childhood Cancer Discovery
A BC study found infant mice infected with a mild virus don’t develop leukemia. Could this work for humans? Read more:...
Nov 6, 2024
FDA Expands Approval for Jylamvo to Children With Acute Lymphoblastic Leukemia
The Food and Drug Administration (FDA) expanded the approval of Jylamvo (methotrexate) to include children with acute lymphoblastic...
Nov 5, 2024
Tracing cancer back to birth uncovers promising biomarkers for prevention, targeted treatment of childhood leukemia
A new study has uncovered molecular markers in blood at birth that are linked to later development of acute lymphoblastic leukemia (ALL),...
Oct 30, 2024