Trial Shows Targeted Treatment for Childhood Brain Tumor is Safe
A Phase I clinical trial demonstrated that a targeted approach to treating a deadly brain tumor in children called diffuse intrinsic...
Apr 7
Experimental treatment borrowed from blood cancer shows promise for pediatric brain tumors
In an early-stage clinical trial, the therapy nearly doubled the expected survival time of young patients. Still, experts caution that...
Mar 24
Study finds pediatric brain tumors rely on different metabolic 'route' to fuel treatment resistance
Rogel researchers, led by Daniel Wahl, M.D., Ph.D., wanted to understand how this mutation affects DIPG tumor metabolism and influences...
Jun 18, 2024
First child cured of rare brain tumor 'offers real hope'
The Belgian boy is the first child in the world to have been cured of brainstem glioma, a particularly brutal cancer, according to the...
Feb 22, 2024
Blocking Immune Molecule Prolongs Survival in Models of the Most Aggressive Childhood Cancer
Researchers demonstrate that TIM-3 inhibition promotes immune memory in diffuse intrinsic stem glioma (DIPG). Read more:...
Oct 13, 2023
New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors
For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain...
Aug 21, 2023
Drug combination discovery may extend life expectancy of children with brain cancer
Newcastle and Hunter-based researchers have discovered a drug combination that could improve the life expectancy of children with brain...
May 30, 2023
Advanced immunotherapy treatment may hold promise for children with brain cancer
WEHI researchers have found promise in treating DIPG with an innovative new immunotherapy treatment, called CAR T therapy. Read more:...
May 11, 2023
Localized delivery of CAR T cells to treat children with brain tumors
Advancements in CAR T cell delivery and B7-H3 targeting enabled researchers to conduct an exploratory clinical trial to evaluate B7-H3...
Apr 20, 2023
From tragedy, a potential pediatric cancer treatment
Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain cancer that often kills within a year of diagnosis. Surgery is almost...
Apr 12, 2023