Rethinking the Development of CAR T-Cell Products for Pediatric Cancer
In a commentary published in the Journal of Clinical Oncology, Claudia Rossig, MD, of the department of pediatric hematology and oncology...
Dec 21, 2023
Promising target for CAR T cells helps cancer trick the immune system
Scientists at St. Jude Children’s Research Hospital showed that GRP78 is a promising but complex target for CAR T–cell immunotherapy...
Dec 7, 2023
NIH researchers develop approach that could help supercharge T-cell therapies against solid tumors
Researchers at the National Institutes of Health have developed a way to potentially increase the effectiveness of T cell–based...
Nov 3, 2023
Solving the Mystery of Long-Lasting Cancer Treatment – Scientists Reveal New Insights
Researchers from UCL, Great Ormond Street Hospital, and the Wellcome Sanger Institute have unveiled findings that shed light on why...
Aug 23, 2023
Advanced immunotherapy treatment may hold promise for children with brain cancer
WEHI researchers have found promise in treating DIPG with an innovative new immunotherapy treatment, called CAR T therapy. Read more:...
May 11, 2023
Localized delivery of CAR T cells to treat children with brain tumors
Advancements in CAR T cell delivery and B7-H3 targeting enabled researchers to conduct an exploratory clinical trial to evaluate B7-H3...
Apr 20, 2023
CAR T cells show promise in neuroblastoma
Using CAR T cells to treat solid tumors is notoriously challenging, but a new study shows impressive responses rates in children with...
Apr 19, 2023
Pediatric Cancer Vaccine May Be ‘Too Good to Be True,’ But More Work Is Needed
Ongoing trials are showing that a cancer vaccine may be able to overcome some of the other issues that are present with immune-based...
Jan 25, 2023
Colin Seaman is the boy with the Harry Potter cells
"While developing a treatment plan, Lee introduced the family to a revolutionary treatment option for some patients with leukemia....
Jan 18, 2023
Could CAR-T-cell therapy offer hope to children with cancer?
The immunotherapy is beginning to show promise in solid tumours, but researchers want more dedicated research in young people. Read...
Dec 23, 2022