Indoximod works to reverse the mechanisms that cancer tumors use to hide from the immune system . The chemotherapy damages the tumor,...

Larotrectinib led to rapid/durable responses and high disease control rates in children with TRK fusion-position central nervous system...

CAR-T cells show promise against pediatric diffuse midline gliomas, brain and spinal cord tumors that are among the deadliest cancers, a...

Research at St. Jude recently showed that the drug capmatinib is effective at crossing the blood-brain-barrier, synergizing with...

Collaborative efforts are revealing critical vulnerabilities in paediatric brain tumours, opening new avenues for targeted therapy. Read...

Diffuse hemispheric glioma, H3G34-mutant (DHG-H3G34) is a type of high-grade glioma that typically affects adolescents and young adults....

Survivors were also 21 times more likely to receive accommodations at school, such as help taking tests, in addition to their worse test...

The discovery of an aggressive genetic group will lead to better patient management of this form of tumour, which urgently requires new...

A drug called ribociclib, currently used to treat breast cancer , could slow the progression of certain pediatric high-grade gliomas, an...

Scientists at St. Jude Children’s Research Hospital found very young children treated for brain tumors were less prepared for school...