Dec 27, 2024
Menin inhibitor clinical trial puts pediatric leukemia patient in remission
“Patient response to revumenib has been good in other clinical trials,” explains Cuglievan. “But it’s also been short-lived when used...
Jul 24, 2024
Gain-of-function mutation reveals new target in pediatric acute myeloid leukemia
Pediatric acute myeloid leukemia (AML) accounts for 20% of all pediatric leukemia cases and is associated with poor outcomes, especially...
Jun 10, 2024
Researchers discover that a type of childhood leukemia originates during fetal development
A team of researchers has demonstrated that some childhood leukemias originate during embryonic development, although they do not...
Feb 8, 2024
‘We now know our enemy’: UBC study offers new hope for treating relapsed childhood leukemia
New therapies have dramatically improved survival rates among children with pediatric acute myeloid leukemia (pAML)—a cancer that starts...
Jan 24, 2024
Molecular ‘super-glue’ shows promise of cancer drug discovery platform
Today, St. Jude Children’s Research Hospital scientists published their work on SJ3149, a compound with broad activity against many...
Jan 18, 2024
Updated genomic landscape for pediatric acute myeloid leukemia enables new treatment possibilities
Scientists at St. Jude Children’s Research Hospital refined and enhanced the classification system for a type of pediatric leukemia using...
Dec 5, 2023
Scientists discover new Achilles heel of leukemia cells
A team led by Jan-Henning Klusmann from the Department of Pediatrics and Dirk Heckl from the Institute for Experimental Pediatric...
Sep 6, 2023
Homoharringtonine May be ‘Better Alternative’ to Etoposide In Pediatric AML
Use of homoharringtonine (HHT) may result in improved responses among patients with pediatric acute myeloid leukemia (AML) compared with...
Jun 19, 2023
New hope for children with rare, high-risk leukaemia thanks to world first research in Manchester
Pioneering research in Manchester has shown dramatic results for treating children with high-risk leukaemia (a type of blood cancer), who...
Mar 20, 2023
Splicing Deregulation Detected and Targeted in Type of Childhood Leukemia
In some children, pediatric acute myeloid leukemia can become resistant to treatment; UC San Diego researchers think they now know why....