Aug 14, 2024
Improved chemokine homing enhances CAR T-cell therapy for osteosarcoma
Scientists at St. Jude Children’s Research Hospital identified chemokines expressed by osteosarcoma that improved CAR T-cell homing, with...
Aug 13, 2024
Drug developed for pancreatic cancer shows promise against most aggressive form of medulloblastoma
A drug that was developed to treat pancreatic cancer has now been shown to increase symptom-free survival in preclinical medulloblastoma...
Aug 9, 2024
Serotonin-producing neurons regulate malignancy in ependymoma brain tumors
A collaborative study published in Nature reveals the functional relevance of tumor-neuron interactions that regulate the growth of...
Aug 8, 2024
UF Health-developed genetic score improves outcomes by personalizing leukemia therapy
Using patients’ own genetics to tailor their chemotherapy regimens appears to improve outcomes in children with acute myeloid leukemia, a...
Jul 30, 2024
Kids From Poorer Families Less Likely to Survive Cancer
Children from poor families are less likely to survive cancer, particularly if they are not white, a new study reports. Read more:...
Jul 29, 2024
New drug hope for children with primary bone cancer
A new drug that potentially works against all main types of primary bone cancer in children has been described by the scientists who...
Jul 26, 2024
Unexpected role of OTX2 drives aggressive medulloblastoma
Researchers revealed an unexpected way in which the protein OTX2 drives the progression of medulloblastoma -- the most common aggressive...
Jul 25, 2024
Pharmacotyping provides a precision medicine blueprint for acute lymphoblastic leukemia treatment
In a report published in Nature Medicine, St. Jude scientists examined how ALL cells respond to different therapeutics in the context of...
Jul 24, 2024
Gain-of-function mutation reveals new target in pediatric acute myeloid leukemia
Pediatric acute myeloid leukemia (AML) accounts for 20% of all pediatric leukemia cases and is associated with poor outcomes, especially...
Jul 23, 2024
Proton therapy improves neurocognitive outcomes of childhood craniopharyngioma
In a recent phase 2 clinical trial for children with craniopharyngioma, researchers at St. Jude found that photon therapy and the more...