Nov 29, 2024
CNIO opens up new research pathways against paediatric cancer Ewing sarcoma by discovering mechanisms that make it more aggressive
A new study led by Ana Losada, head of the Chromosomal Dynamics Group at Spain’s National Cancer Research Centre (CNIO), identifies...
Nov 28, 2024
Larotrectinib Is Promising for Pediatric TRK Fusion-Positive CNS Tumors
Larotrectinib led to rapid/durable responses and high disease control rates in children with TRK fusion-position central nervous system...
Nov 27, 2024
Researchers identify gene signature for high-risk form of T-cell acute lymphoblastic leukemia
Researchers from Children's Hospital of Philadelphia (CHOP) have discovered the underlying biology that identifies a subset of patients...
Nov 26, 2024
If My Dying Daughter Could Face Her Mortality, Why Couldn’t the Rest of Us?
"In pediatric cancer care, which has an understandable emphasis on cure, advances that have brought families hope can often mean survival...
Nov 18, 2024
FDA Grants Rare Pediatric Designation to Elraglusib for Ewing Sarcoma
The FDA granted a rare pediatric disease designation to elraglusib (9-ING-41), a novel GSK-3β inhibitor, as a potential therapeutic...
Nov 15, 2024
Self-reported screening can reduce distressing symptoms for pediatric patients with cancer
Regular, self-reported symptom screening was associated with reduced symptom burden when compared with usual care for pediatric patients...
Nov 14, 2024
Cell therapy fights lethal childhood brain cancer in Stanford Medicine trial
CAR-T cells show promise against pediatric diffuse midline gliomas, brain and spinal cord tumors that are among the deadliest cancers, a...
Nov 12, 2024
Increased Surveillance Recommended for Children at Risk for Hematopoietic Malignancy Predisposition
Children with a genetic risk of developing myelodysplastic syndromes (MDS) and other hematopoietic malignancies (HM), such as leukemias...
Nov 8, 2024
Targeted therapy and radiation synergize in pediatric high-grade glioma
Research at St. Jude recently showed that the drug capmatinib is effective at crossing the blood-brain-barrier, synergizing with...
Nov 7, 2024
Even 15 Years Later, Childhood Cancer Survivors More Likely to Develop Leukemia
Childhood cancer survivors are more likely than the general population to develop subsequent leukemia, even 15 years or more after their...